Vaccinia virus E10R protein is associated with the membranes of intracellular mature virions and has a role in morphogenesis.

doi:10.1006/viro.2000.0656

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Article

Vaccinia virus E10R protein is associated with the membranes of intracellular mature virions and has a role in morphogenesis.

Virology - 5 Dec 2000

Senkevich T G, Weisberg A S, Moss B

Abstract excerpt

This study provides the initial biochemical, microscopic, and genetic characterization of the product of the vaccinia virus E10R gene, which belongs to the ERV1/ALR family of eukaryotic proteins, is conserved in all poxviruses and has homologs in other cytoplasmic DNA viruses. DNA encoding a short epitope tag was appended to the C-terminus of the 95-amino-acid open-reading frame without affecting virus...

Topics

Animals
Cell Cycle
Cell Line
Cell Membrane
Electrophoresis, Polyacrylamide Gel
Isopropyl Thiogalactoside
Microscopy, Immunoelectron
Mutation
Vaccinia virus
Viral Proteins
Virion
Virus Replication

Source

Open in PubMed

Identifiers

PMID: 11112499
DOI: 10.1006/viro.2000.0656

Provenance

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