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From Crescent to Mature Virion: Vaccinia Virus Assembly and Maturation

7 Oct 2014

Abstract excerpt

Vaccinia virus (VACV) has achieved unprecedented success as a live viral vaccine for smallpox which mitigated eradication of the disease. Vaccinia virus has a complex virion morphology and recent advances have been made to answer some of the key outstanding questions, in particular, the origin and biogenesis of the virion membrane, the transformation from immature virion (IV) to mature virus (MV), and the role of...

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PMID: 25296112
DOI: 10.3390/v6103787

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