Vaccinia virus WR gene A5L is required for morphogenesis of mature virions.

doi:10.1128/JVI.73.6.4590-4599.1999

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Vaccinia virus WR gene A5L is required for morphogenesis of mature virions.

Journal of virology - 1 Jun 1999

Williams O, Wolffe E J, Weisberg A S, Merchlinsky M

Abstract excerpt

The vaccinia virus WR A5L open reading frame (corresponding to open reading frame A4L in vaccinia virus Copenhagen) encodes an immunodominant late protein found in the core of the vaccinia virion. To investigate the role of this protein in vaccinia virus replication, we have constructed a recombinant virus, vA5Li, in which the endogenous gene has been deleted and an inducible copy of the A5 gene dependent on...

Topics

Cell Line
DNA, Viral
Genes, Viral
Morphogenesis
Mutation
Open Reading Frames
Vaccinia virus
Viral Proteins
Virion
Virus Replication

Source

Open in PubMed Open full text

Identifiers

PMID: 10233918
DOI: 10.1128/JVI.73.6.4590-4599.1999
PMCID: PMC112500

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics