Article
Involucrin-claudin-6 tail deletion mutant (CDelta206) transgenic mice: a model of delayed epidermal permeability barrier formation and repair.
Disease models & mechanisms - 1 Jan 2000
Enikanolaiye Adebola, Larivière Nathalie, Troy Tammy-Claire, Arabzadeh Azadeh, Atasoy Elif, Turksen Kursad
Abstract excerpt
Preterm birth is a major global health problem that results in a large number of infant deaths, many of which are attributable to the complications of an immature epidermal permeability barrier (EPB), for which there is currently no effective therapeutic option. The mammalian EPB is formed during development and is essential for survival as it maintains thermoregulation and hydration, and provides a defense...
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