Article
Delayed epidermal permeability barrier formation and hair follicle aberrations in Inv-Cldn6 mice.
Mechanisms of development - 1 Jun 2005
Troy Tammy-Claire, Rahbar Ramtin, Arabzadeh Azadeh, Cheung Robert Man-Kit, Turksen Kursad
Abstract excerpt
Homozygous mice overexpressing Claudin-6 (Cldn6) exhibit a perturbation in the epidermal differentiation program leading to a defective epidermal permeability barrier (EPB) and dehydration induced death ensuing within 48 h of birth [Turksen, K., Troy, T.C., 2002. Permeability barrier dysfunction...
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