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Article

Genetic targeting of the endoderm with claudin-6CreER.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Feb 2008

Anderson William J, Zhou Qiao, Alcalde Victor, Kaneko Osamu F, Blank Leah J, Sherwood Richard I, Guseh J Sawalla, Rajagopal Jayaraj, Melton Douglas A

Abstract excerpt

A full description of the ontogeny of the beta cell would guide efforts to generate beta cells from embryonic stem cells (ESCs). The first step requires an understanding of definitive endoderm: the genes and signals responsible for its specification, proliferation, and patterning. This report describes a global marker of definitive endoderm, Claudin-6 (Cldn6). We report its expression in early development with...

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Identifiers

PMID: 18213590
DOI: 10.1002/dvdy.21437
PMCID: PMC2665265

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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