Article
Rap1p is a negative regulator of the RAP1 gene.
Current genetics - 31 Jul 1996
Graham I R, Chambers A
Abstract excerpt
The promoter of the RAP1 gene contains four potential binding sites for Rap1p, located between the UAS and the RNA initiation site. We have confirmed that three of these sites are recognised by Rap1p in vitro. Different combinations of the three sites were then mutated to abolish Rap1p binding, and the effect of these mutations on promoter activity was determined. When all three Rap1p sites were mutated, the...
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