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Article

Conserved amino acid residues in C-terminus of PERIOD 2 are involved in interaction with CRYPTOCHROME 1.

Biochimica et biophysica acta - 1 Apr 2010

Tomita Tatsunosuke, Miyazaki Koyomi, Onishi Yoshiaki, Honda Shinya, Ishida Norio, Oishi Katsutaka

Abstract excerpt

We investigated the amino acid sequences of rat PERIOD2 (rPER2) that are required for interaction with CRYPTOCHROME1 (CRY1) to understand the molecular mechanism of the circadian clock. Co-immunoprecipitation assays using various C-terminal fragments of rPER2 with internal deletions revealed that...

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Source

Identifiers

PMID: 20100521
DOI: 10.1016/j.bbamcr.2010.01.012

Genes

CRY1
PER2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20100521-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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