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Article

The GABA(A)-receptor γ2 (GABRG2) gene in obsessive-compulsive disorder.

Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) - 1 Dec 2009

Richter Margaret A, Zai Gwyneth, McBride Joanna C, Mundo Emanuela, Swinson Richard P, Kennedy James L

Abstract excerpt

OBJECTIVE: The γ-aminobutyric acid type A (GABA(A)) system may be implicated in obsessive-compulsive disorder, based on its major role in modulation of anxiety and its function as the principal inhibitory neurotransmitter system in the cortex. In addition, glutamatergic/GABAergic mechanisms appear to play a role in the pathophysiology of obsessive-compulsive disorder, making the GABA(A) receptor-γ2 (GABργ2) gene...

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Share to Diagnostic and Statistical Manual of Mental Disorders
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20098824
DOI: 10.1590/s1516-44462009000400008

Genes

GABRG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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