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Article

Association of gamma-aminobutyric acid A receptor α2 gene (GABRA2) with alcohol use disorder.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Mar 2014

Li Dawei, Sulovari Arvis, Cheng Chao, Zhao Hongyu, Kranzler Henry R, Gelernter Joel

Abstract excerpt

Gamma-aminobutyric acid (GABA) is a major inhibitory neurotransmitter in mammalian brain. GABA receptor are involved in a number of complex disorders, including substance abuse. No variants of the commonly studied GABA receptor genes that have been associated with substance dependence have been determined to be functional or pathogenic. To reconcile the conflicting associations with substance dependence traits,...

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Source

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Identifiers

PMID: 24136292
DOI: 10.1038/npp.2013.291
PMCID: PMC3924525

Genes

GABRA2
GABRA6
GABRG2
GABRA1
GABRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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