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Article

Association of a glutamate (NMDA) subunit receptor gene (GRIN2B) with obsessive-compulsive disorder: a preliminary study.

Psychopharmacology - 1 Aug 2004

Arnold Paul D, Rosenberg David R, Mundo Emanuela, Tharmalingam Subi, Kennedy James L, Richter Margaret A

Abstract excerpt

RATIONALE: Recent investigation suggests that a reversible glutamatergically mediated thalamocortical-striatal dysfunction may serve as a reliable pathophysiological and treatment response marker for obsessive-compulsive disorder (OCD). We postulated that N-methyl- d-aspartate (NMDA) receptors we...

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Identifiers

PMID: 15083261
DOI: 10.1007/s00213-004-1847-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15083261-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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