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Article

Caveolae‐mediated entry of <i>Salmonella typhimurium</i> into senescent nonphagocytotic host cells

20 Jan 2010

Abstract excerpt

Elderly individuals have an increased susceptibility to microbial infections because of age-related anatomical, physiological, and environmental factors. However, the mechanism of aging-dependent susceptibility to infection is not fully understood. Here, we found that caveolae-dependent endocytosis is elevated in senescent cells. Thus, we focused on the implications of caveolae-dependent endocytosis using...

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PMID: 20096033
DOI: 10.1111/j.1474-9726.2010.00554.x

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