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The LC3 recruitment mechanism is separate from Atg9L1-dependent membrane formation in the autophagic response against<i>Salmonella</i>

28 Apr 2011

Abstract excerpt

Salmonella develops into resident bacteria in epithelial cells, and the autophagic machinery (Atg) is thought to play an important role in this process. In this paper, we show that an autophagosome-like double-membrane structure surrounds the Salmonella still residing within the Salmonella-containing vacuole (SCV). This double membrane is defective in Atg9L1- and FAK family-interacting protein of 200 kDa...

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PMID: 21525242
DOI: 10.1091/mbc.e10-11-0893

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