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<i>Salmonella</i> Typhimurium effector SseI regulates host peroxisomal dynamics to acquire lysosomal cholesterol for better intracellular growth

2023-02-27

Abstract excerpt

Intracellular Salmonella resides and multiplies in cholesterol-rich specialized compartment called Salmonella -containing vacuoles (SCVs) and avoids fusion with acidic lysosomes. Given, lysosomes are primary organelle that redistributes LDL derived cholesterol to other organelles; we questioned how lysosomal cholesterol can be transported to SCV. We demonstrate here that peroxisomes are recruited to SCVs in huma...

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Identifiers and source

Literature Corpus work
2b4b16d7-fc39-5398-8876-93243bae64bd
DOI
10.1101/2023.02.27.530266
Open publication

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<i>Salmonella</i> Typhimurium effector SseI regulates host peroxisomal dynamics to acquire lysosomal cholesterol for better intracellular growthDOI 10.1101/2023.02.27.530266
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