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Article

A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium.

The Journal of cell biology - 29 Jan 2007

Smith Adam C, Heo Won Do, Braun Virginie, Jiang Xiuju, Macrae Chloe, Casanova James E, Scidmore Marci A, Grinstein Sergio, Meyer Tobias, Brumell John H

Abstract excerpt

Members of the Rab guanosine triphosphatase (GTPase) family are key regulators of membrane traffic. Here we examined the association of 48 Rabs with model phagosomes containing a non-invasive mutant of Salmonella enterica serovar Typhimurium (S. Typhimurium). This mutant traffics to lysosomes and allowed us to determine which Rabs localize to a maturing phagosome. In total, 18 Rabs associated with maturing...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17261845
DOI: 10.1083/jcb.200611056
PMCID: PMC2063952

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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