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Article

Atypical hemolytic uremic syndrome.

Orphanet journal of rare diseases - 8 Sept 2011

Loirat Chantal, Frémeaux-Bacchi Véronique

Abstract excerpt

Hemolytic uremic syndrome (HUS) is defined by the triad of mechanical hemolytic anemia, thrombocytopenia and renal impairment. Atypical HUS (aHUS) defines non Shiga-toxin-HUS and even if some authors include secondary aHUS due to Streptococcus pneumoniae or other causes, aHUS designates a primary disease due to a disorder in complement alternative pathway regulation. Atypical HUS represents 5 -10% of HUS in...

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Identifiers

PMID: 21902819
DOI: 10.1186/1750-1172-6-60
PMCID: PMC3198674

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