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Article

[Atypical HUS caused by complement-related abnormalities].

[Rinsho ketsueki] The Japanese journal of clinical hematology - 1 Feb 2015

Yoshida Yoko, Matsumoto Masanori

Abstract excerpt

Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure. The term aHUS was historically used to distinguish this disorder from Shiga-toxin producing Escherichia coli (STEC)-HUS. Many aHUS cases (approximately 70%) are reportedly caused by uncontrolled complement activation due to genetic mutations in the...

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Source

Identifiers

PMID: 25765799
DOI: 10.11406/rinketsu.56.185

Genes

ADAMTS13
CFB
CFH
CFI
DGKE
THBD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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