[Atypical hemolytic-uremic syndrome related to abnormalities within the complement system].

doi:10.1016/j.revmed.2009.09.039

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Article

[Atypical hemolytic-uremic syndrome related to abnormalities within the complement system].

La Revue de medecine interne - 1 Apr 2011

Frémeaux-Bacchi V, Fakhouri F, Roumenina L, Dragon-Durey M-A, Loirat C

Abstract excerpt

Hemolytic uremic syndrome (HUS) is a thrombotic microangiopathy (TMA) disorder characterised by the association of haemolytic anaemia, thrombocytopenia and acute renal failure. Atypical forms (non-shigatoxin related forms) may be familial or sporadic, frequently with relapses and most of them lead to end stage renal failure. During the last years, different groups have demonstrated genetic predisposition to...

Topics

Atypical Hemolytic Uremic Syndrome
Complement C3
Complement Factor B
Complement Factor H
Complement System Proteins
Fibrinogen
Hemolytic-Uremic Syndrome
Humans
Immunologic Factors
Membrane Cofactor Protein
Mutation
Plasma Exchange
Risk Factors
Treatment Outcome

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PMID: 21376430
DOI: 10.1016/j.revmed.2009.09.039

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