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Article

An upstream insulator regulates DLK1 imprinting in AML.

Blood - 18 Mar 2010

Khoury Haytham, Suarez-Saiz Fernando, Wu Samantha, Minden Mark D

Abstract excerpt

DLK1 is an imprinted gene on chromosome 14. Using informative coding single nucleotide polymorphisms, we found DLK1 expression to be monoallelic in normal bone marrow, whereas it was biallelic in 76% of acute myeloid leukemia (AML) overexpressing DLK1 (61% of all AML). Quantitative methylation an...

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Share to Calcium-Binding Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Leukemic

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Share to Intercellular Signaling Peptides and Proteins

Share to Leukemia, Myeloid, Acute

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Source

Identifiers

PMID: 20089961
DOI: 10.1182/blood-2009-03-212746

Genes

DLK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20089961-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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