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Article

Deregulation of small non-coding RNAs at the DLK1-DIO3 imprinted locus predicts lung cancer patient outcome.

Oncotarget - 6 Dec 2016

Enfield Katey S S, Martinez Victor D, Marshall Erin A, Stewart Greg L, Kung Sonia H Y, Enterina Jhon R, Lam Wan L

Abstract excerpt

Deregulation of the imprinted DLK1-DIO3 locus at chromosome 14q32.1-14q32.31 has been associated with developmental and respiratory disorders, including cancer. In lung cancer, deregulation of imprinting at DLK1-DIO3 was recently described in smokers. Deregulated expression of a microRNA (miRNA) cluster mapping to this locus was also associated with patient outcome, suggesting the importance of this locus to lung...

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Source

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Identifiers

PMID: 27829231
DOI: 10.18632/oncotarget.13133
PMCID: PMC5348368

Genes

DIO3
DLK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Deregulation of small non-coding RNAs at the DLK1-DIO3 imprinted locus predicts lung cancer patient outcome.PMID 27829231Read ↗

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