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Article

Mitochondrial dysfunction confers resistance to multiple drugs in Caenorhabditis elegans.

Molecular biology of the cell - 15 Mar 2010

Zubovych Iryna O, Straud Sarah, Roth Michael G

Abstract excerpt

In a previous genetic screen for Caenorhabditis elegans mutants that survive in the presence of an antimitotic drug, hemiasterlin, we identified eight strong mutants. Two of these were found to be resistant to multiple toxins, and in one of these we identified a missense mutation in phb-2, which...

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Identifiers

PMID: 20089839
DOI: 10.1091/mbc.e09-08-0673
PMCID: PMC2836976

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20089839-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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