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Article

AMPK-mediated regulation of transcription in skeletal muscle.

Clinical science (London, England : 1979) - 26 Jan 2010

McGee Sean L, Hargreaves Mark

Abstract excerpt

Skeletal muscle phenotype plays a critical role in human performance and health, and skeletal muscle oxidative capacity is a key determinant of exercise tolerance. More recently, defective muscle oxidative metabolism has been implicated in a number of conditions associated with the metabolic syndrome, cardiovascular disease and muscle-wasting disorders. AMPK (AMP-activated protein kinase) is a critical regulator...

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Share to AMP-Activated Protein Kinases
Share to Enzyme Activation
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscle, Skeletal

Share to Neovascularization, Physiologic

Share to Phenotype

Share to Signal Transduction

Share to Transcription, Genetic

Source

Identifiers

PMID: 20088830
DOI: 10.1042/CS20090533

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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