Promoter-specific regulation of PPARGC1A gene expression in human skeletal muscle

Abstract excerpt

The goal of this study was to identify unknown transcription start sites of the PPARGC1A (PGC-1α) gene in human skeletal muscle and investigate the promoter-specific regulation of PGC-1α gene expression in human skeletal muscle. Ten amateur endurance-trained athletes performed high- and low-intensity exercise sessions (70 min, 70% or 50% o2max). High-throughput RNA sequencing and exon-exon junction mapping were...

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