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Article

AMPK: a key sensor of fuel and energy status in skeletal muscle.

Physiology (Bethesda, Md.) - 1 Feb 2006

Hardie D Grahame, Sakamoto Kei

Abstract excerpt

Contraction induces marked metabolic changes in muscle, and the AMP-activated protein kinase (AMPK) is a good candidate to explain these effects. Recent work using a muscle-specific knockout of the upstream kinase, LKB1, has confirmed that the LKB1-->AMPK cascade is the signaling pathway responsible for many of these effects.

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Source

Identifiers

PMID: 16443822
DOI: 10.1152/physiol.00044.2005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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