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Article

AMP-activated protein kinase regulation and action in skeletal muscle during exercise.

Biochemical Society transactions - 1 Feb 2003

Musi N, Yu H, Goodyear L J

Abstract excerpt

Physical exercise increases muscle glucose uptake, enhances insulin sensitivity and leads to fatty acid oxidation in muscle. The AMP-activated protein kinase (AMPK) is an energy-sensing enzyme that is strongly activated during muscle contraction due to acute decreases in ATP/AMP and phosphocreatine/creatine ratios. Accumulating evidence suggests that AMPK plays an important role in mediating these metabolic...

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Source

Identifiers

PMID: 12546683
DOI: 10.1042/bst0310191

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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