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Article

Role of AMP-activated protein kinase in the coordinated expression of genes controlling glucose and lipid metabolism in mouse white skeletal muscle.

Diabetologia - 1 Nov 2005

Long Y C, Barnes B R, Mahlapuu M, Steiler T L, Martinsson S, Leng Y, Wallberg-Henriksson H, Andersson L, Zierath J R

Abstract excerpt

AIMS/HYPOTHESIS: AMP-activated protein kinase (AMPK) regulates metabolic adaptations in skeletal muscle. The aim of this study was to investigate whether AMPK modulates the expression of skeletal muscle genes that have been implicated in lipid and glucose metabolism under fed or fasting conditions. METHODS: Two genetically modified animal models were used: AMPK gamma3 subunit knockout mice (Prkag3(-/-)) and...

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Identifiers

PMID: 16237515
DOI: 10.1007/s00125-005-1962-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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