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Article

Fragile X Syndrome and Alzheimer's Disease: Another story about APP and beta-amyloid.

Current Alzheimer research - 1 May 2010

Malter J S, Ray B C, Westmark P R, Westmark C J

Abstract excerpt

As the mechanisms underlying neuronal development and degeneration become clarified, a number of common effectors and signaling pathways are becoming apparent. Here we describe the identification of Abeta, long considered a pathologic mediator of Alzheimers Disease and Down Syndrome, as similarly...

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Share to Amyloid beta-Peptides
Share to Amyloid beta-Protein Precursor
Share to Excitatory Amino Acid Antagonists

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fragile X Mental Retardation Protein

Share to Fragile X Syndrome

Share to Glutamic Acid

Share to Receptor, Metabotropic Glutamate 5

Share to Receptors, Metabotropic Glutamate

Source

Open in PubMed Open full text

Identifiers

PMID: 20088809
DOI: 10.2174/156720510791050957
PMCID: PMC4256041

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20088809-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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