Article
Genetic variation in the vitamin D receptor (VDR) and the vitamin D-binding protein (GC) and risk for colorectal cancer: results from the Colon Cancer Family Registry.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 2010
Poynter Jenny N, Jacobs Elizabeth T, Figueiredo Jane C, Lee Won H, Conti David V, Campbell Peter T, Levine A Joan, Limburg Paul, Le Marchand Loic, Cotterchio Michelle, Newcomb Polly A, Potter John D, Jenkins Mark A, Hopper John L, Duggan David J, Baron John A, Haile Robert W
Abstract excerpt
Epidemiologic evidence supports a role for vitamin D in colorectal cancer (CRC) risk. Variants in vitamin D-related genes might modify the association between vitamin D levels and CRC risk. In this analysis, we did a comprehensive evaluation of common variants in the vitamin D receptor (VDR) and the vitamin D-binding protein (GC; group-specific component) genes using a population-based case-unaffected sibling...
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