Article
Genetic variation in calcium-sensing receptor and risk for colon cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2008
Dong Linda M, Ulrich Cornelia M, Hsu Li, Duggan David J, Benitez Debbie S, White Emily, Slattery Martha L, Caan Bette J, Potter John D, Peters Ulrike
Abstract excerpt
BACKGROUND: Experimental and epidemiologic studies have suggested that high calcium intake is associated with decreased colon cancer risk, yet very limited data are available for candidate genes in the calcium-vitamin D pathway and colon cancer risk. To address this, we evaluated whether calcium-sensing receptor (CASR) single-nucleotide polymorphisms are associated with colon cancer risk. We also examined...
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