Article
Lack of associations between Vitamin D metabolism-related gene variants and risk of colorectal cancer.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2014
Mahmoudi Touraj, Karimi Khatoon, Arkani Maral, Farahani Hamid, Nobakht Hossein, Dabiri Reza, Asadi Asadollah, Vahedi Mohsen, Zali Mohammad Reza
Abstract excerpt
PURPOSE: With regard to the protective effect of vitamin D against colorectal cancer (CRC), we evaluated genetic variants that might influence vitamin D metabolism: vitamin D receptor (VDR), vitamin D binding protein (GC), vitamin D 25-hydroxylase (CYP2R1), and vitamin D 25-hydroxy 1-alpha hydroxylase (CYP27B1). MATERIALS AND METHODS: A total of 657 subjects, including 303 cases with CRC and 354 controls were...
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