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Article

Vitamin D Receptor Gene Polymorphism and the Risk of Colorectal Cancer: A Nested Case-Control Study.

PloS one - 1 Jan 2016

Budhathoki Sanjeev, Yamaji Taiki, Iwasaki Motoki, Sawada Norie, Shimazu Taichi, Sasazuki Shizuka, Yoshida Teruhiko, Tsugane Shoichiro

Abstract excerpt

Epidemiological and experimental evidence suggest that vitamin D is protective against the risk of colorectal cancer. Polymorphisms in the gene encoding vitamin D receptor (VDR), which mediates most of the known cellular effects of vitamin D, have been suggested to alter this association. Here, using a tag SNP approach, we comprehensively evaluated the role of common genetic variants in VDR and their interaction...

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Source

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Identifiers

PMID: 27736940
DOI: 10.1371/journal.pone.0164648
PMCID: PMC5063384

Genes

VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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