Article
Serum vitamin D concentration, vitamin D-related polymorphisms, and colorectal cancer risk.
International journal of cancer - 15 Jul 2023
Li Jiaoyuan, Qin Shifan, Zhang Shanshan, Lu Yifan, Shen Qian, Cheng Liming, Zhong Rong
Abstract excerpt
Serum 25-hydroxyvitamin D (25(OH)D) has been demonstrated to be associated with risk of colorectal cancer (CRC). However, it remains unclear whether this association was modified by vitamin D-related polymorphisms. We evaluated association of serum 25(OH)D concentration with CRC risk among 403 170 participants from UK Biobank Project. Two variants of vitamin D binding protein (VDBP), rs4588 and rs7041, were...
Topics
- Humans
- Polymorphism, Single Nucleotide
- Vitamin D
- Vitamins
- Receptors, Calcitriol
- Genotype
