Article
Dimer-dimer stacking interactions are important for nucleic acid binding by the archaeal chromatin protein Alba.
The Biochemical journal - 15 Mar 2010
Jelinska Clare, Petrovic-Stojanovska Biljana, Ingledew W John, White Malcolm F
Abstract excerpt
Archaea use a variety of small basic proteins to package their DNA. One of the most widespread and highly conserved is the Alba (Sso10b) protein. Alba interacts with both DNA and RNA in vitro, and we show in the present study that it binds more tightly to dsDNA (double-stranded DNA) than to either ssDNA (single-stranded DNA) or RNA. The Alba protein is dimeric in solution, and forms distinct ordered complexes...
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