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Article

Comparative analysis of genome-wide protein-DNA interactions across domains of life reveals unique binding patterns for hypersaline archaeal histones

2022-03-23

Abstract excerpt

<h4>ABSTRACT</h4> DNA-binding proteins with roles in chromatin architecture and transcriptional regulation are present in all three domains of life. Histones package DNA and regulate gene expression in eukaryotes, and find their evolutionary origin in the domain of life Archaea. Previously characterised archaeal histones have a somewhat conserved functional role in nucleosome formation and DNA packaging. However,...

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Literature Corpus work
dddd3115-bc2a-5ae2-bfb0-e33fe98ff6d5
DOI
10.1101/2022.03.22.485428
Open publication

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Comparative analysis of genome-wide protein-DNA interactions across domains of life reveals unique binding patterns for hypersaline archaeal histonesDOI 10.1101/2022.03.22.485428
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