Article
Comparative analysis of genome-wide protein-DNA interactions across domains of life reveals unique binding patterns for hypersaline archaeal histones
2022-03-23
Abstract excerpt
<h4>ABSTRACT</h4> DNA-binding proteins with roles in chromatin architecture and transcriptional regulation are present in all three domains of life. Histones package DNA and regulate gene expression in eukaryotes, and find their evolutionary origin in the domain of life Archaea. Previously characterised archaeal histones have a somewhat conserved functional role in nucleosome formation and DNA packaging. However,...
Identifiers and source
- Literature Corpus work
- dddd3115-bc2a-5ae2-bfb0-e33fe98ff6d5
- DOI
- 10.1101/2022.03.22.485428
