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Article

The Rad9A checkpoint protein is required for nuclear localization of the claspin adaptor protein.

Cell cycle (Georgetown, Tex.) - 1 Feb 2010

Sierant Megan L, Archer Nicole E, Davey Scott K

Abstract excerpt

The interaction between the 911 complex, via Rad9A, and Claspin is required for activation of the Chk1-mediated checkpoint response, along with ATR, TopBp1, and the 911 clamp loader complex Rad17/RFC. Despite the importance of the Rad9A-Claspin interaction in the cell cycle, this interaction has...

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Source

Identifiers

PMID: 20081369
DOI: 10.4161/cc.9.3.10553

Genes

ATR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20081369-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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The Rad9A checkpoint protein is required for nuclear localization of the claspin adaptor protein.PMID 20081369Read ↗

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Drf1-dependent kinase interacts with Claspin through a conserved protein motif.Semantic proximity Read ↗

SCFbetaTrCP-mediated degradation of Claspin regulates recovery from the DNA replication checkpoint response.Semantic proximity Read ↗

Rad9/53BP1 promotes crossover recombination DNA repair by limiting the Sgs1 and Mph1 helicasesSemantic proximity Read ↗

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