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Article

Drf1-dependent kinase interacts with Claspin through a conserved protein motif.

The Journal of biological chemistry - 23 Apr 2010

Gold Daniel A, Dunphy William G

Abstract excerpt

The Dbf4/Drf1-dependent kinase (DDK) is required for the initiation of DNA replication in eukaryotes. Another protein, Claspin, mediates the activation of a cellular checkpoint response to stalled replication forks and is also a regulator of replication. In this study, we found that DDK phosphory...

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Identifiers

PMID: 20190277
DOI: 10.1074/jbc.M109.077370
PMCID: PMC2857117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20190277-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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