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Article

Effects of G994T in the Lp-PLA2 gene on the plasma oxidized LDL level and carotid intima-media thickness in Japanese: the Shimane study.

American journal of hypertension - 1 Jul 2009

Wang Tao, Karino Kenji, Yamasaki Masayuki, Zhang Yan, Masuda Junichi, Yamaguchi Shuhei, Shiwaku Kuninori, Nabika Toru

Abstract excerpt

BACKGROUND: A single-nucleotide polymorphism (SNP), G994T, in the lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) gene is known to have a potent influence on the activity of the enzyme. As this enzyme hydrolyzes oxidized low-density lipoprotein (oxLDL), which is an important player in atherogenesis, the present study evaluated effects of the G994T genotype on the oxLDL level as well as on intima media...

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Identifiers

PMID: 19373214
DOI: 10.1038/ajh.2009.70

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Effects of G994T in the Lp-PLA2 gene on the plasma oxidized LDL level and carotid intima-media thickness in Japanese: the Shimane study.PMID 19373214Read ↗

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