Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of A379V variant of the Lp-PLA 2 gene on Lp-PLA 2 activity and markers of oxidative stress and endothelial function in Koreans.

Journal of thrombosis and thrombolysis - 1 Nov 2014

Chae Jey Sook, Kwak Jung Hyun, Kim Minjoo, Shin Kyoung Hun, Lee Sang-Hyun, Jeong Tae-Sook, Lee Jong Ho

Abstract excerpt

A379V variant in the lipoprotein-associated phospholipase A2 (Lp-PLA 2) gene is known to be functional, but there are contradicting data concerning the A379V polymorphism, Lp-PLA2 activity and cardiovascular disease risk. We determined the interplay between A379V SNP, Lp-PLA2 activity, and markers of oxidative stress and endothelial function with and without the effect of V279F variant. 3,220 unrelated and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 1-Alkyl-2-acetylglycerophosphocholine Esterase
Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to Endothelium, Vascular

Share to Enzyme Activation

Share to Genetic Markers

Share to Genetic Variation

Share to Oxidative Stress

Source

Identifiers

PMID: 24682749
DOI: 10.1007/s11239-014-1074-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of A379V variant of the Lp-PLA 2 gene on Lp-PLA 2 activity and markers of oxidative stress and endothelial function in Koreans.PMID 24682749Read ↗

Effects of V279F in the Lp-PLA(2) gene on markers of oxidative stress and inflammation in Koreans.Semantic proximity Read ↗

The Val279Phe variant of the lipoprotein-associated phospholipase A2 gene is associated with catalytic activities and cardiovascular disease in Korean men.Semantic proximity Read ↗

Carriage of the V279F null allele within the gene encoding Lp-PLA₂ is protective from coronary artery disease in South Korean males.Semantic proximity Read ↗

A phenome-wide association study of a lipoprotein-associated phospholipase A2 loss-of-function variant in 90 000 Chinese adults.Semantic proximity Read ↗

Comprehensive evaluation of genetic and environmental factors influencing the plasma lipoprotein-associated phospholipase A2 activity in a Japanese population.Semantic proximity Read ↗

Possible effects of lipoprotein-associated phospholipase A2 single-nucleotide polymorphisms on cardiovascular risk in patients with preeclampsia.Semantic proximity Read ↗

PLA2G7 genotype, lipoprotein-associated phospholipase A2 activity, and coronary heart disease risk in 10 494 cases and 15 624 controls of European Ancestry.Semantic proximity Read ↗

Lipoprotein-associated phospholipase A2 gene V279F polymorphisms and coronary heart disease: a meta-analysis.Semantic proximity Read ↗

Association between the Ala379Val variant of the lipoprotein associated phospholipase A2 and risk of myocardial infarction in the north and south of Europe.Semantic proximity Read ↗

Lipoprotein-associated phospholipase A2 and risk of incident peripheral arterial disease: Findings from The Atherosclerosis Risk in Communities study (ARIC).Semantic proximity Read ↗

Lp-PLA2 activity and PLA2G7 A379V genotype in patients with diabetes mellitus.Semantic proximity Read ↗

Association of Lp-PLA2 G994T gene polymorphism with risk of ischemic stroke in Chinese population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.