Article
Nitric oxide repression of Nanog promotes mouse embryonic stem cell differentiation.
Cell death and differentiation - 1 Jun 2010
Mora-Castilla S, Tejedo J R, Hmadcha A, Cahuana G M, Martín F, Soria B, Bedoya F J
Abstract excerpt
Exposure of mouse embryonic stem (mES) cells to high concentrations of chemical nitric oxide (NO) donors promotes differentiation, but the mechanisms involved in this process at the gene expression level are poorly defined. In this study we report that culture of mES cells in the presence of 0.25...
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