Article
Analysis of tissue-specific lacZ mutations induced by N-nitrosodibenzylamine in transgenic mice.
Carcinogenesis - 1 Nov 1997
Jiao J, Douglas G R, Gingerich J D, Soper L M
Abstract excerpt
N-Nitrosodibenzylamine (NDBzA) is a contaminant found frequently in rubber baby bottle nipples and pacifiers. To evaluate more fully the mutagenic potential and analyse the molecular nature of possible mutations induced in vivo, we have studied the mutagenicity of NDBzA in vivo using the MutaMouse system. NDBzA, suspended in olive oil, was administered orally once to male mice at different doses (0, 30, 100, 425...
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