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Article

Genetic variations in the mycophenolate mofetil target enzyme are associated with acute GVHD risk after related and unrelated hematopoietic cell transplantation.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Feb 2012

Cao Weijie, Xiao Haowen, Lai Xiaoyu, Luo Yi, Shi Jimin, Tan Yamin, Zheng Weiyan, He Jingsong, Xie Wanzhuo, Li Li, Ye Xiujin, Yu Xiaohong, Lin Maofang, Cai Zhen, Huang He

Abstract excerpt

Inosine monophosphate dehydrogenase (IMPDH) is the target enzyme of mycophenolate mofetil (MMF). Single nucleotide polymorphisms (SNPs) in the IMPDH1 gene are reportedly relevant to acute rejection in renal transplant patients receiving MMF. The objective of this study was to identify the impact of IMPDH1 gene polymorphisms on the outcomes of allogeneic hematopoietic stem cell transplantation (allo-HSCT). Four...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21745452
DOI: 10.1016/j.bbmt.2011.06.014

Genes

IMPDH1

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Genetic variations in the mycophenolate mofetil target enzyme are associated with acute GVHD risk after related and unrelated hematopoietic cell transplantation.PMID 21745452Read ↗

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