Article
An SGS3-like protein functions in RNA-directed DNA methylation and transcriptional gene silencing in Arabidopsis.
The Plant journal : for cell and molecular biology - 1 Apr 2010
Zheng Zhimin, Xing Yu, He Xin-Jian, Li Wenbo, Hu Yuanlei, Yadav Sudesh Kumar, Oh JeeEun, Zhu Jian-Kang
Abstract excerpt
RNA-directed DNA methylation (RdDM) is an important epigenetic mechanism for silencing transgenes and endogenous repetitive sequences such as transposons. The RD29A promoter-driven LUCIFERASE transgene and its corresponding endogenous RD29A gene are hypermethylated and silenced in the Arabidopsis DNA demethylase mutant ros1. By screening for second-site suppressors of ros1, we identified the RDM12 locus. The...
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