Article
Epigenetic memory marks determine epiallele stability at loci targeted by de novo DNA methylation.
Nature plants - 1 Jun 2020
Li Jingwen, Yang Dong-Lei, Huang Huan, Zhang Guiping, He Li, Pang Jia, Lozano-Durán Rosa, Lang Zhaobo, Zhu Jian-Kang
Abstract excerpt
It is generally assumed that DNA methylation changes at genomic regions targeted by the de novo RNA-directed DNA methylation (RdDM) pathway are unstable. Here, we show that RdDM targets in Arabidopsis can be classified into two groups on the basis of whether there is remethylation following the restoration of NRPD1 function in nrpd1 mutant plants-remethylable loci and non-remethylable loci. In contrast to the...
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