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FDDM1 and FDDM2, Two SGS3-like Proteins, Function as a Complex to Affect DNA Methylation in Arabidopsis.

Genes - 12 Feb 2022

Li Shengjun, Yang Weilong, Liu Yunfeng, Li Guangyong, Liu Xiang, Liu Yaling, Alfano James R, Zhang Chi, Yu Bin

Abstract excerpt

DNA methylation is an important epigenetic modification required for the specific regulation of gene expression and the maintenance of genome stability in plants and animals. However, the mechanism of DNA demethylation remains largely unknown. Here, we show that two SGS3-like proteins, FACTOR OF DNA DEMETHYLATION 1 (FDDM1) and FDDM2, negatively affect the DNA methylation levels at ROS1-dependend DNA loci in...

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Identifiers

PMID: 35205382
DOI: 10.3390/genes13020339
PMCID: PMC8872474

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FDDM1 and FDDM2, Two SGS3-like Proteins, Function as a Complex to Affect DNA Methylation in Arabidopsis.PMID 35205382Read ↗

A subgroup of SGS3-like proteins act redundantly in RNA-directed DNA methylation.Semantic proximity Read ↗

The DNA- and RNA-binding protein FACTOR of DNA METHYLATION 1 requires XH domain-mediated complex formation for its function in RNA-directed DNA methylation.Semantic proximity Read ↗

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