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Article

Different evolutionary histories of the coagulation factor VII gene in human populations?

Annals of human genetics - 1 Jan 2010

Athanasiadis Georgios, Esteban Esther, Gayà-Vidal Magdalena, Dugoujon Jean-Michel, Moschonas Nicholas, Chaabani Hassen, Bissar-Tadmouri Nisrine, Harich Nourdin, Stoneking Mark, Moral Pedro

Abstract excerpt

Immoderate blood clotting constitutes a risk factor for cardiovascular disease in modern industrialised societies, but is believed to have conferred a survival advantage, i.e. faster recovery from bleeding, on our ancestors. Here, we investigate the evolutionary history of the Coagulation Factor VII gene (F7) by analysing five cardiovascular-risk-associated mutations from the F7 promoter and nine neutral...

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PMID: 20059471
DOI: 10.1111/j.1469-1809.2009.00557.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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