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Article

Genetic architecture of the F7 gene in a Spanish population: implication for mapping complex diseases and for functional assays.

Clinical genetics - 1 May 2006

Sabater-Lleal M, Almasy L, Martínez-Marchán E, Martínez-Sánchez E, Souto R, Blangero J, Souto Jc, Fontcuberta J, Soria J M

Abstract excerpt

Delineating the genetic variability of loci coding for complex diseases helps to understand the individual variation in disease susceptibility and drug response. We present the allelic architecture of the F7 gene. This gene is the major determinant of FVII plasma levels, and these plasma levels constitute an important intermediate risk factor for cardiovascular disease. As part of the Genetic Analysis of...

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PMID: 16650081
DOI: 10.1111/j.1399-0004.2006.00608.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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