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Article

The implications of patterns in HIV diversity for neutralizing antibody induction and susceptibility.

Current opinion in HIV and AIDS - 1 Sept 2009

Korber Bette, Gnanakaran S

Abstract excerpt

PURPOSE OF REVIEW: Designing an HIV vaccine capable of eliciting broadly cross-reactive neutralizing antibodies is an extraordinarily difficult challenge. Here we focus on the implications of HIV diversity for vaccine design, detailing the impact of levels of variation in epitopes of known potent neutralizing antibodies, and summarizing patterns of overall variation in regional domains within gp120. Strategies...

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Share to AIDS Vaccines
Share to Antibodies, Neutralizing
Share to Epitopes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to HIV Antibodies

Share to HIV Envelope Protein gp120

Share to HIV Infections

Source

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Identifiers

PMID: 20048705
DOI: 10.1097/COH.0b013e32832f129e
PMCID: PMC6426297

Provenance

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