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Article

Greb1 is required for axial elongation and segmentation in vertebrate embryos.

Biology open - 11 Feb 2020

Prajapati Ravindra Singh, Mitter Richard, Vezzaro Annalisa, Ish-Horowicz David

Abstract excerpt

During vertebrate embryonic development, the formation of axial structures is driven by a population of stem-like cells that reside in a region of the tailbud called the chordoneural hinge (CNH). We have compared the mouse CNH transcriptome with those of surrounding tissues and shown that the CNH and tailbud mesoderm are transcriptionally similar, and distinct from the presomitic mesoderm. Amongst CNH-enriched...

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Identifiers

PMID: 31988092
DOI: 10.1242/bio.047290
PMCID: PMC7044451

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