Article
Polymorphisms in gene encoding TRPV1-receptor involved in pain perception are unrelated to chronic pancreatitis.
BMC gastroenterology - 24 Dec 2009
van Esch Aura A J, Lamberts Mark P, te Morsche René H M, van Oijen Martijn G H, Jansen Jan B M J, Drenth Joost P H
Abstract excerpt
BACKGROUND: The major clinical feature in chronic pancreatitis is pain, but the genetic basis of pancreatic pain in chronic pancreatitis is poorly understood. The transient receptor potential vanilloid receptor 1 (TRPV1) gene has been associated with pain perception, and genetic variations in TRPV1 may modify the presence and phenotype of chronic pancreatitis. The aim of our study was to investigate the genetic...
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