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Article

Common calcium-sensing receptor (CASR) gene variants do not modify risk for chronic pancreatitis in a Hungarian cohort.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] - 1 Oct 2021

Takáts Amanda, Berke Gergő, Szentesi Andrea, Farkas Gyula, Izbéki Ferenc, Erőss Bálint, Czakó László, Vincze Áron, Hegyi Péter, Sahin-Tóth Miklós, Hegyi Eszter

Abstract excerpt

The calcium-sensing receptor (CASR) is expressed in the pancreas where it might regulate calcium concentrations in pancreatic secretions. Two independent studies reported conflicting results claiming that commonly occurring missense variants of the CASR gene are risk factors for chronic pancreatitis (CP). Here, we attempted to replicate the association between CASR variants and CP. We analyzed 337 patients and...

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation, Missense

Share to Pancreatitis, Chronic

Share to Polymorphism, Single Nucleotide

Share to Receptors, Calcium-Sensing

Share to Sequence Analysis, DNA

Source

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Identifiers

PMID: 34481716
DOI: 10.1016/j.pan.2021.08.012
PMCID: PMC8663126

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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